you can use it for the protection circuit. But input signal logic level should also be between 4-5 volt. It may be from a microcontroller or any other device.
LIN pin 12 is an input signal for low side Mosfet driver output.But input signal logic level should be between 4-5 volt. HIN pin 10 is an input signal for high side MOSFET driver output.But if you used voltage less than 4 volts it may not give you the required result.
When hen input to low side at pin 12 Lin is low, LO output will be equal to the value of VSS and it means zero. Because when an input to the low side at pin 12 Lin is high, LO output will be equal to the value of Vcc voltage at pin 3 with respect to Vss and COM pin. It is at the same potential as ground VSS pin 13.